Clinical and Translational Oncology Utrecht University

Programme Structure

Curriculum:

• Novel tumor culture protocols and sophisticated mouse models have greatly improved the quality of translational research. 

• The clinical impact of studies using these platforms will, in all likelihood, be considerably higher than those based on traditional cell culture models. 

• The novel model systems are also increasingly being used for studying basic aspects of tumor biology, metastasis, tumor recurrence following therapy, and therapy resistance. 

• In addition, the rapid development of ‘omics’ technologies that document changes in tumor DNA, RNA, proteins and metabolites allow for an in-depth analysis of the tumors and the genetic background of individual patients. 

• The large datasets that are generated with these techniques requires implementation of Bioinformatics in the research structure. Ultimately these developments should lead to true personalized cancer therapy.